This study characterizes the proportion of clients served by AIDS Institute-funded providers who reported social determinants of health-related needs across nine domains (i.e., housing, food security, transportation, financial security, employment, health literacy, social isolation, stigma, disability) between April 1, 2020, and September 30, 2024. This study also examined differences in social determinants of health-related needs for client by HIV status while accounting for age, gender identity, race and economic status.